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	gallbladder cancer

Disease ID	596
Disease	gallbladder cancer
Definition	A primary or metastatic malignant neoplasm that affects the gallbladder. Representative examples include carcinoma, lymphoma, melanoma, and sarcoma.
Synonym	bladder cancer, gall bladder cancers, gall cancer gallbladder cancer of gallbladder cancer of the gallbladder cancer, gall bladder cancer, gallbladder cancers, gall bladder cancers, gallbladder gall bladder cancer gall bladder cancers gallbladder ca gallbladder ca (disorder) gallbladder cancers gallbladder malignant neoplasm gallbladder tumor or cancer gallbladder--cancer malig neo gallbladder malignant gallbladder neoplasm malignant gallbladder tumor malignant neoplasm of gallbladder malignant neoplasm of the gallbladder malignant tumor of gallbladder malignant tumor of gallbladder (disorder) malignant tumor of the gallbladder malignant tumour of gallbladder of gallbladder cancer
DOID	DOID:3121 DOID:4948
ICD10	ICD10CM:C23
UMLS	C0153452
SNOMED-CT	SNOMEDCT_US_2016_09_01:363353009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:48) C0008350 \| gallstones \| 5 C0040053 \| thrombus \| 3 C0494165 \| liver metastasis \| 3 C0008325 \| cholecystitis \| 3 C0686619 \| lymph node metastases \| 2 C0007140 \| carcinosarcoma \| 2 C0011847 \| diabetes \| 2 C0022354 \| obstructive jaundice \| 2 C0235974 \| pancreatic cancer \| 1 C0751498 \| sigmoid colon cancer \| 1 C0238137 \| gallbladder adenoma \| 1 C0016085 \| filariasis \| 1 C0001430 \| adenoma \| 1 C1140680 \| ovarian ca \| 1 C0206702 \| klatskin tumor \| 1 C1337035 \| xanthogranulomatous cholecystitis \| 1 C0750952 \| biliary tract cancer \| 1 C0494165 \| hepatic metastases \| 1 C0024586 \| carcinoid syndrome \| 1 C0018802 \| congestive heart failure \| 1 C0220650 \| brain metastasis \| 1 C0740277 \| bile duct cancer \| 1 C0008350 \| gallstone \| 1 C1334028 \| hilar cholangiocarcinoma \| 1 C0494165 \| hepatic metastasis \| 1 C0016977 \| gallbladder diseases \| 1 C0014118 \| endocarditis \| 1 C0011633 \| dermatomyositis \| 1 C0017536 \| giardiasis \| 1 C0024623 \| gastric cancers \| 1 C0029408 \| osteoarthritis \| 1 C0162871 \| abdominal aortic aneurysm \| 1 C0001418 \| adenocarcinomas \| 1 C0011849 \| diabetes mellitus \| 1 C0948265 \| metabolic syndrome \| 1 C0948303 \| peritoneal carcinoma \| 1 C0016977 \| gallbladder disease \| 1 C0041466 \| enteric fever \| 1 C0494165 \| liver metastases \| 1 C0024623 \| gastric cancer \| 1 C0087086 \| thrombi \| 1 C0019204 \| hepatocellular carcinoma \| 1 C0221390 \| nonbacterial thrombotic endocarditis \| 1 C0024623 \| stomach cancer \| 1 C0030305 \| pancreatitis \| 1 C0008350 \| cholelithiasis \| 1 C0878500 \| epithelial dysplasia \| 1 C0001339 \| acute pancreatitis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) 152330 \| CNTN4 \| GWASCAT 1630 \| DCC \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:5) 338 \| APOB \| CIPHER 2944 \| GSTM1 \| CIPHER 2947 \| GSTM3 \| CIPHER 2950 \| GSTP1 \| CIPHER 2952 \| GSTT1 \| CIPHER
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:126) 105 \| ADARB2 \| 1.646 \| DISEASES 84740 \| AFAP1-AS1 \| 1.61 \| DISEASES 174 \| AFP \| 2.514 \| DISEASES 307 \| ANXA4 \| 1.762 \| DISEASES 9826 \| ARHGEF11 \| 1.385 \| DISEASES 438 \| ASMT \| 1.27 \| DISEASES 648 \| BMI1 \| 1.08 \| DISEASES 685 \| BTC \| 3.534 \| DISEASES 10950 \| BTG3 \| 1.126 \| DISEASES 842 \| CASP9 \| 1.826 \| DISEASES 100507056 \| CCAT1 \| 1.125 \| DISEASES 55036 \| CCDC40 \| 1.846 \| DISEASES 885 \| CCK \| 1.955 \| DISEASES 960 \| CD44 \| 2.156 \| DISEASES 1012 \| CDH13 \| 1.128 \| DISEASES 1029 \| CDKN2A \| 3.111 \| DISEASES 1045 \| CDX2 \| 1.673 \| DISEASES 55743 \| CHFR \| 1.59 \| DISEASES 25792 \| CIZ1 \| 1.286 \| DISEASES 1164 \| CKS2 \| 1.237 \| DISEASES 1192 \| CLIC1 \| 1.642 \| DISEASES 9022 \| CLIC3 \| 2.007 \| DISEASES 643911 \| CRNDE \| 1.636 \| DISEASES 1499 \| CTNNB1 \| 2.49 \| DISEASES 1586 \| CYP17A1 \| 1.464 \| DISEASES 1543 \| CYP1A1 \| 2.743 \| DISEASES 1654 \| DDX3X \| 1.754 \| DISEASES 1806 \| DPYD \| 1.391 \| DISEASES 1778 \| DYNC1H1 \| 1.184 \| DISEASES 9166 \| EBAG9 \| 2.567 \| DISEASES 1978 \| EIF4EBP1 \| 1.037 \| DISEASES 2045 \| EPHA7 \| 2 \| DISEASES 2100 \| ESR2 \| 1.448 \| DISEASES 51013 \| EXOSC1 \| 1.191 \| DISEASES 356 \| FASLG \| 1.144 \| DISEASES 26269 \| FBXO8 \| 1.598 \| DISEASES 2248 \| FGF3 \| 1.463 \| DISEASES 2272 \| FHIT \| 2.674 \| DISEASES 2300 \| FOXL1 \| 1.389 \| DISEASES 2305 \| FOXM1 \| 1.352 \| DISEASES 2632 \| GBE1 \| 2.03 \| DISEASES 2665 \| GDI2 \| 1.541 \| DISEASES 728441 \| GGT2 \| 1.584 \| DISEASES 10755 \| GIPC1 \| 1.028 \| DISEASES 2873 \| GPS1 \| 1.336 \| DISEASES 2885 \| GRB2 \| 1.287 \| DISEASES 57000 \| GSN-AS1 \| 1.314 \| DISEASES 3065 \| HDAC1 \| 1.082 \| DISEASES 3068 \| HDGF \| 1.801 \| DISEASES 55733 \| HHAT \| 1.695 \| DISEASES 285943 \| HOXA-AS2 \| 2.359 \| DISEASES 10553 \| HTATIP2 \| 2.07 \| DISEASES 64423 \| INF2 \| 2.507 \| DISEASES 3880 \| KRT19 \| 1.705 \| DISEASES 3855 \| KRT7 \| 2.735 \| DISEASES 55353 \| LAPTM4B \| 3.447 \| DISEASES 3927 \| LASP1 \| 1.928 \| DISEASES 286826 \| LIN9 \| 1.29 \| DISEASES 4043 \| LRPAP1 \| 1.583 \| DISEASES 84328 \| LZIC \| 2.472 \| DISEASES 346389 \| MACC1 \| 1.608 \| DISEASES 378938 \| MALAT1 \| 1.967 \| DISEASES 57708 \| MIER1 \| 1.146 \| DISEASES 4318 \| MMP9 \| 2.393 \| DISEASES 645249 \| MNX1-AS1 \| 3.299 \| DISEASES 92140 \| MTDH \| 2.171 \| DISEASES 2475 \| MTOR \| 1.34 \| DISEASES 4582 \| MUC1 \| 3.158 \| DISEASES 4583 \| MUC2 \| 3.089 \| DISEASES 4585 \| MUC4 \| 2.656 \| DISEASES 4586 \| MUC5AC \| 2.406 \| DISEASES 4588 \| MUC6 \| 2.223 \| DISEASES 4609 \| MYC \| 1.881 \| DISEASES 140609 \| NEK7 \| 2.057 \| DISEASES 4795 \| NFKBIL1 \| 1.193 \| DISEASES 51701 \| NLK \| 2.323 \| DISEASES 4831 \| NME2 \| 2.506 \| DISEASES 101241892 \| NPTN-IT1 \| 3.163 \| DISEASES 9971 \| NR1H4 \| 1.017 \| DISEASES 93034 \| NT5C1B \| 1.273 \| DISEASES 142 \| PARP1 \| 1.755 \| DISEASES 5091 \| PC \| 1.457 \| DISEASES 23089 \| PEG10 \| 1.594 \| DISEASES 5230 \| PGK1 \| 1.229 \| DISEASES 5241 \| PGR \| 1.056 \| DISEASES 80012 \| PHC3 \| 1.079 \| DISEASES 57661 \| PHRF1 \| 1.229 \| DISEASES 5514 \| PPP1R10 \| 1.424 \| DISEASES 5567 \| PRKACB \| 1.483 \| DISEASES 8842 \| PROM1 \| 1.82 \| DISEASES 112476 \| PRRT2 \| 1.292 \| DISEASES 5728 \| PTEN \| 1.745 \| DISEASES 5743 \| PTGS2 \| 2.534 \| DISEASES 9698 \| PUM1 \| 1.738 \| DISEASES 11186 \| RASSF1 \| 1.689 \| DISEASES 83593 \| RASSF5 \| 1.105 \| DISEASES 6091 \| ROBO1 \| 2.078 \| DISEASES 6281 \| S100A10 \| 1.673 \| DISEASES 6280 \| S100A9 \| 3.173 \| DISEASES 6336 \| SCN10A \| 1.154 \| DISEASES 5268 \| SERPINB5 \| 2.459 \| DISEASES 2810 \| SFN \| 1.062 \| DISEASES 6443 \| SGCB \| 3.898 \| DISEASES 137868 \| SGCZ \| 1.908 \| DISEASES 9058 \| SLC13A2 \| 1.753 \| DISEASES 284111 \| SLC13A5 \| 1.76 \| DISEASES 2030 \| SLC29A1 \| 1.125 \| DISEASES 4089 \| SMAD4 \| 1.9 \| DISEASES 23583 \| SMUG1 \| 3.474 \| DISEASES 677841 \| SNORA74B \| 3.079 \| DISEASES 100642175 \| SPRY4-IT1 \| 1.497 \| DISEASES 6714 \| SRC \| 1.281 \| DISEASES 63826 \| SRR \| 1.931 \| DISEASES 23635 \| SSBP2 \| 1.627 \| DISEASES 3925 \| STMN1 \| 1.414 \| DISEASES 10460 \| TACC3 \| 1.839 \| DISEASES 4070 \| TACSTD2 \| 1.422 \| DISEASES 10732 \| TCFL5 \| 3.197 \| DISEASES 7048 \| TGFBR2 \| 1.788 \| DISEASES 84000 \| TMPRSS13 \| 1.398 \| DISEASES 93492 \| TPTE2 \| 2.647 \| DISEASES 55000 \| TUG1 \| 1.29 \| DISEASES 7360 \| UGP2 \| 1.363 \| DISEASES 7422 \| VEGFA \| 2.255 \| DISEASES 9948 \| WDR1 \| 1.638 \| DISEASES 6935 \| ZEB1 \| 1.077 \| DISEASES
Locus	(Waiting for update.)

Disease ID	596
Disease	gallbladder cancer
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:26) HP:0002664 \| Neoplasia \| 17 HP:0000952 \| Yellow skin \| 7 HP:0001081 \| Gallstones \| 7 HP:0001082 \| Cholecystitis \| 3 HP:0012126 \| Gastric cancer \| 2 HP:0000718 \| Aggressive behaviour \| 2 HP:0030153 \| Cholangiocarcinoma \| 2 HP:0012531 \| Pain \| 2 HP:0010474 \| Bladder stones \| 1 HP:0001735 \| Acute pancreatitis \| 1 HP:0002894 \| Neoplasia of the pancreas \| 1 HP:0001402 \| Hepatocellular carcinoma \| 1 HP:0030731 \| Carcinoma \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0001945 \| Fever \| 1 HP:0100890 \| Cyst of the ductus choledochus \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0003077 \| Hyperlipidemia \| 1 HP:0004953 \| Abdominal aortic aneurysm \| 1 HP:0011899 \| Hyperfibrinogenemia \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0002902 \| Hyponatremia \| 1 HP:0100570 \| Carcinoid tumor \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0002758 \| Osteoarthritis \| 1 HP:0100584 \| Endocarditis \| 1

Disease ID	596
Disease	gallbladder cancer
Manually Symptom	UMLS \| Name(Total Manually Symptoms:13) C2203646 \| jaundice C1333963 \| hepatic carcinoid tumor C0947622 \| gallstones C0940937 \| precancerous lesions C0850639 \| premalignant lesion C0686619 \| lymph node metastases C0400979 \| biliary obstruction C0267878 \| mirizzi syndrome C0221390 \| nonbacterial thrombotic endocarditis C0153676 \| pulmonary metastases C0149631 \| biliary reflux C0017536 \| giardiasis C0000727 \| surgical abdomen
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:6) C0008350 \| gallstones \| 5 C0022346 \| jaundice \| 3 C0008325 \| cholecystitis \| 3 C0017536 \| giardiasis \| 1 C0221390 \| nonbacterial thrombotic endocarditis \| 1 C0686619 \| lymph node metastases \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:73)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1042522	17531965	1543	CYP1A1	umls:C0153452	BeFree	These results suggest that the Val allele of CYP1A1 Ile462Val polymorphism and the Pro allele of TP53 Arg72Pro polymorphism contribute to an increased risk of GBC among Japanese women and men, respectively.	0.002171535	2007	TP53	17	7676154	G	T,C
rs1042522	18990008	7157	TP53	umls:C0153452	BeFree	We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.	0.007057489	2008	TP53	17	7676154	G	T,C
rs1048943	17531965	1543	CYP1A1	umls:C0153452	BeFree	These results suggest that the Val allele of CYP1A1 Ile462Val polymorphism and the Pro allele of TP53 Arg72Pro polymorphism contribute to an increased risk of GBC among Japanese women and men, respectively.	0.002171535	2007	CYP1A1	15	74720644	T	G,C,A
rs1052133	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	OGG1;CAMK1	3	9757089	C	G
rs1052133	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	OGG1;CAMK1	3	9757089	C	G
rs1052133	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	OGG1;CAMK1	3	9757089	C	G
rs1052133	17417784	4968	OGG1	umls:C0153452	BeFree	hOGG1 Ser326Cys polymorphism and susceptibility to gallbladder cancer in a Chinese population.	0.001085767	2007	OGG1;CAMK1	3	9757089	C	G
rs1052133	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	OGG1;CAMK1	3	9757089	C	G
rs1052133	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	OGG1;CAMK1	3	9757089	C	G
rs1052133	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	OGG1;CAMK1	3	9757089	C	G
rs11540654	18990008	7157	TP53	umls:C0153452	BeFree	We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary.	0.007057489	2008	TP53	17	7676040	C	T,G,A
rs11540654	17531965	1543	CYP1A1	umls:C0153452	BeFree	These results suggest that the Val allele of CYP1A1 Ile462Val polymorphism and the Pro allele of TP53 Arg72Pro polymorphism contribute to an increased risk of GBC among Japanese women and men, respectively.	0.002171535	2007	TP53	17	7676040	C	T,G,A
rs11887534	21062971	64241	ABCG8	umls:C0153452	BeFree	Carriers of the ABCG8 haplotype C-C (rs4148217-rs11887534) had a 4.16-fold (95% CI 1.71-10.1) risk of gallbladder cancer compared with those carrying the C-G haplotype.	0.000542884	2011	ABCG5;ABCG8	2	43839108	G	A,C
rs17577	24863943	4318	MMP9	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.000542884	2014	MMP9	20	46014472	G	A,C
rs17577	24863943	4313	MMP2	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.001085767	2014	MMP9	20	46014472	G	A,C
rs1799793	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	ERCC2	19	45364001	C	T
rs1799793	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	ERCC2	19	45364001	C	T
rs1799793	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	ERCC2	19	45364001	C	T
rs1799793	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	ERCC2	19	45364001	C	T
rs1799793	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	ERCC2	19	45364001	C	T
rs1799793	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	ERCC2	19	45364001	C	T
rs20417	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	PTGS2;PACERR	1	186681189	C	G
rs20417	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	PTGS2;PACERR	1	186681189	C	G
rs20417	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	PTGS2;PACERR	1	186681189	C	G
rs20417	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	PTGS2;PACERR	1	186681189	C	G
rs20417	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	PTGS2;PACERR	1	186681189	C	G
rs20417	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	PTGS2;PACERR	1	186681189	C	G
rs2072668	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	OGG1	3	9756456	C	G
rs2072668	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	OGG1	3	9756456	C	G
rs2072668	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	OGG1	3	9756456	C	G
rs2072668	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	OGG1	3	9756456	C	G
rs2072668	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	OGG1	3	9756456	C	G
rs2072668	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	OGG1	3	9756456	C	G
rs2274223	24863943	4318	MMP9	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.000542884	2014	PLCE1	10	94306584	A	G
rs2274223	24863943	4313	MMP2	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.001085767	2014	PLCE1	10	94306584	A	G
rs2303426	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	MSH2	2	47403411	C	A,G
rs2303426	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	MSH2	2	47403411	C	A,G
rs2303426	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	MSH2	2	47403411	C	A,G
rs2303426	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	MSH2	2	47403411	C	A,G
rs2303426	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	MSH2	2	47403411	C	A,G
rs2303426	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	MSH2	2	47403411	C	A,G
rs2695121	24863943	4313	MMP2	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.001085767	2014	NR1H2	19	50377484	T	C
rs2695121	24863943	4318	MMP9	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.000542884	2014	NR1H2	19	50377484	T	C
rs3546355	24863943	4318	MMP9	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.000542884	2014	NA	NA	NA	NA	NA
rs3546355	24863943	4313	MMP2	umls:C0153452	BeFree	Multidimensional reduction analysis revealed LXR-β (rs3546355 G > A, rs2695121 T > C), MMP-2 (-1306 C > T), MMP-9 (R668Q), and PLCE1 rs2274223 A > G to be key players in GBC causation (p < 0.001, CVC = 7/10).	0.001085767	2014	NA	NA	NA	NA	NA
rs3808607	20005541	1581	CYP7A1	umls:C0153452	BeFree	CYP7A1 (-204 A>C; rs3808607 and -469 T>C; rs3824260) promoter polymorphisms and risk of gallbladder cancer in North Indian population.	0.000542884	2010	CYP7A1	8	58500365	G	T
rs3824260	20005541	1581	CYP7A1	umls:C0153452	BeFree	CYP7A1 (-204 A>C; rs3808607 and -469 T>C; rs3824260) promoter polymorphisms and risk of gallbladder cancer in North Indian population.	0.000542884	2010	CYP7A1	8	58500631	A	G
rs3834129	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	CASP8	2	201232809	AGTAAG	-
rs3834129	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	CASP8	2	201232809	AGTAAG	-
rs3834129	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	CASP8	2	201232809	AGTAAG	-
rs3834129	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	CASP8	2	201232809	AGTAAG	-
rs3834129	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	CASP8	2	201232809	AGTAAG	-
rs3834129	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	CASP8	2	201232809	AGTAAG	-
rs4148217	21062971	64241	ABCG8	umls:C0153452	BeFree	Carriers of the ABCG8 haplotype C-C (rs4148217-rs11887534) had a 4.16-fold (95% CI 1.71-10.1) risk of gallbladder cancer compared with those carrying the C-G haplotype.	0.000542884	2011	ABCG8	2	43872294	C	A,G,T
rs4986791	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	TLR4	9	117713324	C	T
rs4986791	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	TLR4	9	117713324	C	T
rs4986791	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	TLR4	9	117713324	C	T
rs4986791	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	TLR4	9	117713324	C	T
rs4986791	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	TLR4	9	117713324	C	T
rs4986791	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	TLR4	9	117713324	C	T
rs6259	19168589	6462	SHBG	umls:C0153452	BeFree	Among women taking oral contraceptives, the effect of SHBG Ex8 + 6 (rs6259) on gallbladder cancer (OR = 6.7, 95% CI = 2.2-20.5; P interaction = 0.001) and stones (OR = 2.3, 95% CI = 1.1-4.9; P-interaction = 0.05) was statistically significant.	0.000271442	2009	SHBG	17	7633209	G	A
rs689466	21283657	2068	ERCC2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	PTGS2;PACERR	1	186681619	T	C
rs689466	21283657	841	CASP8	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	PTGS2;PACERR	1	186681619	T	C
rs689466	21283657	7097	TLR2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	PTGS2;PACERR	1	186681619	T	C
rs689466	21283657	4968	OGG1	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.001085767	2011	PTGS2;PACERR	1	186681619	T	C
rs689466	21283657	7099	TLR4	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000542884	2011	PTGS2;PACERR	1	186681619	T	C
rs689466	21283657	4436	MSH2	umls:C0153452	BeFree	Single locus analysis by logistic regression showed association of MSH2 IVS1+9G>C (rs2303426), ERCC2 Asp312Asn (rs1799793), OGG1 Ser326Cys (rs1052133), OGG1 IVS4-15C>G (rs2072668), CASP8 -652 6N ins/del (rs3834129), PTGS2 -1195G>A (rs689466), PTGS2 -765G>C (rs20417), TLR4 Ex4+936C>T (rs4986791) and TLR2 -196 to -174del polymorphisms with GBC risk.	0.000271442	2011	PTGS2;PACERR	1	186681619	T	C
rs693	20082485	338	APOB	umls:C0153452	BeFree	Genetic variants involved in gallstone formation such as the apolipoprotein B rs693 and CETP rs708272 polymorphisms may be related to the risk of developing GBC in Chilean women.	0.003452799	2010	APOB	2	21009323	G	A
rs708272	20082485	338	APOB	umls:C0153452	BeFree	Genetic variants involved in gallstone formation such as the apolipoprotein B rs693 and CETP rs708272 polymorphisms may be related to the risk of developing GBC in Chilean women.	0.003452799	2010	CETP	16	56962376	G	A
rs743572	24687554	1586	CYP17A1	umls:C0153452	BeFree	CYP17 polymorphism (rs743572) is associated with increased risk of gallbladder cancer in tobacco users.	0.002909916	2014	CYP17A1	10	102837395	A	G,T
rs743572	24687554	9360	PPIG	umls:C0153452	BeFree	However, in the case-only analysis, CYP rs743572 showed association with increased risk of GBC in tobacco users at hetero genotype and dominant models, as compared to non-user GBC patients.	0.000542884	2014	CYP17A1	10	102837395	A	G,T
rs7504990	22318345	1630	DCC	umls:C0153452	GWASCAT	A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.	0.120542884	2012	DCC	18	52991406	T	C
rs975334	22318345	152330	CNTN4	umls:C0153452	GWASCAT	A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.	0.12	2012	CNTN4	3	2804632	G	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:66)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	247636518	rs4472786	G	A	rs4472786	22318345	6.20E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
2	21825860	rs918897	A	G	rs918897	22318345	2.46E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	NA
2	134350570	rs6715224	C	T	rs6715224	22318345	4.33E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
2	197669189	rs2289380	C	T	rs2289380	22318345	3.02E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	C2orf66
2	197673035	rs7580839	C	T	rs7580839	22318345	9.65E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	C2orf66
2	197715078	rs1866186	G	A	rs1866186	22318345	9.65E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	PGAP1
2	197747960	rs636258	C	T	rs636258	22318345	9.69E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	PGAP1
2	212157104	rs4632271	T	C	rs4632271	22318345	8.49E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
2	223872737	rs1371647	G	A	rs1371647	22318345	1.06E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
2	241835543	rs10206101	A	C	rs10206101	22318345	2.03E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	C2orf54
2	241838504	rs4630763	G	A,T	rs4630763	22318345	3.46E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G,A	NA
3	2846316	rs975334	G	A	rs975334	22318345	9.00E-07	NA	8.3	[3.57-19.26]	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	rs975334-C	Research Support, Non-U.S. Gov't	T	CNTN4
3	153354747	rs13321012	A	G	rs13321012	22318345	4.26E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	NA
4	67126645	rs434623	G	A	rs434623	22318345	1.79E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
4	67140834	rs1397755	G	A	rs1397755	22318345	4.18E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
4	67160054	rs12645235	G	A	rs12645235	22318345	4.59E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
4	67169493	rs12642661	C	T	rs12642661	22318345	4.45E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
4	67186241	rs6820508	T	C	rs6820508	22318345	4.14E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
4	67188696	rs17087008	G	A	rs17087008	22318345	4.04E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
4	67228874	rs12642012	T	C	rs12642012	22318345	9.08E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
4	89316509	rs17790893	A	G	rs17790893	22318345	8.17E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	HERC6
5	93810208	rs6869388	T	C	rs6869388	22318345	7.00E-06	NA	72.7	[11.19-472.10]	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	rs6869388-C	Research Support, Non-U.S. Gov't	C	KIAA0825
5	107781571	rs918399	C	T	rs918399	22318345	4.71E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
5	135323434	rs30737	T	G	rs30737	22318345	2.23E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
5	160099440	rs11135109	G	T	rs11135109	22318345	6.41E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	ATP10B
5	160106482	rs17058110	C	T	rs17058110	22318345	2.57E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	ATP10B
7	35627351	rs343719	A	C	rs343719	22318345	4.58E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
7	35646526	rs4640967	A	C	rs4640967	22318345	4.63E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	NA
7	35646980	rs10279330	C	T	rs10279330	22318345	4.63E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
7	109052359	rs10953607	G	A	rs10953607	22318345	5.43E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
7	109081747	rs11975565	T	C	rs11975565	22318345	4.51E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
7	109152711	rs10953615	A	G	rs10953615	22318345	9.00E-06	NA	7.51	[3.08-18.30]	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	rs10953615-C	Research Support, Non-U.S. Gov't	A	NA
7	109160687	rs10499977	C	T	rs10499977	22318345	9.08E-06	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
7	109161891	rs12705610	T	C	rs12705610	22318345	9.08E-06	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA
8	221671	rs17206521	G	A	rs17206521	22318345	7.12E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
8	18501321	rs11785801	T	C	rs11785801	22318345	2.56E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	PSD3
9	26694888	rs13294589	A	G	rs13294589	22318345	2.00E-06	NA	12.78	[4.43-36.83]	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	rs13294589-G	Research Support, Non-U.S. Gov't	G	NA
9	99487607	rs1596359	C	T	rs1596359	22318345	1.68E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	NA
9	99509624	rs10114863	C	T	rs10114863	22318345	1.68E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
9	101883808	rs1571590	A	G	rs1571590	22318345	7.12E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	TGFBR1
10	87764778	rs10887544	A	C	rs10887544	22318345	4.59E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	GRID1
11	117388932	rs11216435	C	T	rs11216435	22318345	7.36E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	DSCAML1
11	126480356	rs493725	C	T	rs493725	22318345	2.79E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	KIRREL3
12	1210884	rs12316126	A	G	rs12316126	22318345	2.50E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	ERC1
13	22734648	rs9578440	A	C	rs9578440	22318345	9.83E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	NA
13	22739748	rs2025302	G	T	rs2025302	22318345	1.49E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
15	34928486	rs7498116	G	A	rs7498116	22318345	8.06E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	NA
17	65710869	rs12453460	G	T	rs12453460	22318345	4.44E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	LOC100507049
18	50466897	rs1943132	G	A	rs1943132	22318345	3.60E-05	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	DCC
18	50517776	rs7504990	T	C	rs7504990	22318345	7.00E-08	NA	6.95	[3.43-14.08]	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	rs7504990-A	Research Support, Non-U.S. Gov't	C	DCC
18	50519527	rs7506663	T	C	rs7506663	22318345	3.67E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	DCC
18	50520733	rs9957080	G	T	rs9957080	22318345	7.46E-08	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	DCC
18	50521566	rs9304437	T	G	rs9304437	22318345	7.46E-08	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	DCC
18	50525557	rs7507060	C	T	rs7507060	22318345	7.46E-08	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	DCC
18	50525840	rs11082960	G	T	rs11082960	22318345	7.46E-08	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	DCC
18	50529637	rs7504512	G	A	rs7504512	22318345	4.21E-08	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	DCC
18	50533671	rs7506454	G	A	rs7506454	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	DCC
18	50534412	rs9944713	C	A	rs9944713	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	DCC
18	50535809	rs7233818	T	C	rs7233818	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	DCC
18	50536604	rs9951405	A	G	rs9951405	22318345	1.45E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	G	DCC
18	50538552	rs4940234	C	A	rs4940234	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	DCC
18	50546319	rs4077283	G	A	rs4077283	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	A	DCC
18	50547105	rs4078289	A	G	rs4078289	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	DCC
18	50547251	rs4078288	G	A	rs4078288	22318345	3.19E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	DCC
18	50547640	rs7504750	C	A	rs7504750	22318345	3.15E-07	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	C	DCC
21	27723281	rs2117454	T	C	rs2117454	22318345	1.36E-04	NA	NA	NA	41 Japanese ancestry cases; 866 Japanese ancestry controls	Japanese(907)	ALL(907)	ASN(907)	ALL(907)	Gallbladder cancer	HPOID:0100575	Neoplasm of the gallbladder	DOID:3121	gallbladder cancer	D005706	Gallbladder Neoplasms	NA	NA	Gallbaldder cancer	NA	Research Support, Non-U.S. Gov't	T	NA

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	596
Disease	gallbladder cancer
Case	(Waiting for update.)